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patents and scientific training activities performed through the supervision of doctoral theses (more than 20 theses read) and divulgation of courses to PhD students and specialised technical personnel.
Since 2009 the group is responsible for the CAbS (Custom Antibody Service) a technological facility created by the group through CSIC and CIBER-BBN and whose aim is to provide services and scientific advice to public and private research centres and companies, in relation to the production of specific antibodies and bioconjugates and the establishment of immunochemical methods.
Regarding the clinical sector, Nb4D is interested in and develops projects in the following areas:
1. Cardiovascular Diseases 2. Infectious Diseases 3. Neurologic and Neurodegenerative Diseases 4. Therapeutic Drug Monitoring 5. Adverse Drug Reactions
Most relevant scientific articles
• Pastells C., Pascual N., Sánchez-Baeza F., Marco M.-P. Immunochemical Determination of Pyocyanin and 1-Hydroxyphenazine as Potential Biomarkers of Pseudomonas aeruginosa Infections. Analytical Chemistry. 2016;88(3):1631-1638.
• Pastells C., Marco M.-P., Merino D., Loza-Álvarez P., Pasquardini L., Lunelli L. et al. Two photon versus one photon fluorescence excitation in whispering gallery mode microresonators. Journal of Luminescence. 2016;170:860-865.
• Salvador J.-P., Marco M.-P. Amperometric Biosensor for Continuous Monitoring Irgarol 1051 in Sea Water. Electroanalysis. 2016;28(8):1833-1838.
• Hassani N.E.A.E., Baraket A., Neto E.T.T., Lee M., Salvador J.-P., Marco M.-P. et al. Novel strategy for sulfapyridine detection using a fully integrated electrochemical Bio-MEMS: Application to honey analysis. Biosensors and Bioelectronics. 2016.
• Roncador G., Engel P., Maestre L., Anderson A.P., Cordell J.L., Cragg M.S. et al. The European antibody network’s practical guide to finding and validating suitable antibodies for research. mAbs. 2016;8(1):27-36.
Highlights
Nb4D continues to work on the development of diagnostic devices to be used in the clinical diagnosis field as well as the food safety and environmental monitoring areas.
The group was awarded a grant from ACCIÓ (Agency for Business Competitiveness) of the Generalitat of Catalonia to provide support to groups who are seeking to be accredited with the TECNIO seal. The aim is to help define and boost our action plans for technology transfer (marketing) while simultaneously preparing the group to achieve higher levels of quality control and subsequently the quality assurance seal from Tecnio.
The project “A new approach for the diagnosis of Pseudomonas aeruginosa infections” has been selected by the CaixaImpulse programme which provides finance to develop the scientific project and work on the valorisation plan while also providing mentors to monitor and support the future project or spin-off.
The group will be host to three Early Stage Researchers as part of the Marie Sklowdowska Curie Actions
whose aim is to enable research focussed organisations to host talented foreign researchers and to create strategic partnerships with leading institutions worldwide. The group is hosting one ESR as part of the ND4ID “New Diagnostics for Infectious Diseases” project. The group will also host 2 ESRs for the FoodSmartphone “Smartphone analysers for on-site testing of food quality and safety”.
The group continues to collaborate with the Pharmasans Labs Inc. (USA) company to develop immunoreagents against biomarkers of neurodegenerative diseases and has begun to develop immunoreagents against pterins, known cofactors used in the biosynthesis of neurotransmittors.
The group has been working on various projects related to clinical diagnosis including the ImmunoQS proejct whose objective is to investigate immunochemical strategies for diagnosis and therapy based on Quorum sensing. The group is also investigating the possible molecular links between diabetes and neurodegenerative diseases.
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Research Groups 75