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leaD reSearcher
Albericio Palomera, Fernando
Universidad de Barcelona
Facultad de Química Dpto. de Química-Física C/ Martí i Franqués, 1 08028 Barcelona
[email protected]
group Website
GROUP MEMBERS
Staff members: Acosta Crespo, Gerardo Alexis | Cristóbal Lecina, Edgar | Pulido Martínez, Daniel Associated members: Álvarez Domingo, Mercedes | Blanco Canosa, Juan Bautista | Lavilla Grifols, Rodolfo | Royo Expósito, Miriam | Spengler, Jan | Tulla Puche, Judit
Contributors: López Ibáñez, Alba | Lorente Crivillé, Adriana | Melgarejo Díaz, Marta | Pulido Villamil, Ximena Carolina
Main lines of research
• Design and synthesis of bioactive low molecular weight compounds and peptides.
• Dendrimers based on defined units of oligoethylene glycol (OEG) as multifunctional systems for the
creation of new biomaterials with application to drug delivery and tissue engineering (osteogenesis).
• Drugs-polymer conjugates based on polyglutamic (PGA), OEG dendrimers and drug-plymer miceles, as
nanomedicine for the advanced colorectal and triple negative breast cancer treatment. Study of the use
of these platforms on monotherapy and combined therapy with or without active targeting.
• Multiple ligands as chemical tools to study various biological processes, for example: G protein-coupled
receptors (GPCRs) oligomerization
• Development of protein drug delivery systems (PEGylation, peptide functionalized nanovesicles) for
substitutive therapy (ie: Fabry diseaseand San Filippo).
• Design and synthesis of gamma peptides with capacity to cross biological barriers, such as the
cytoplasmatic membrane of eukaryotic cells and parasites (Leishmania) and the blood brain barrier
(BBB).
• Development of target peptides for colorectal and triple negative breast cancer tissues.
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PROGRAMMES
Nanomedicine