Page 100 - CIBERBBN-2015-eng

Research groups
Biomaterials Group
Programme: Biomaterials & Advanced Therapies / Nanomedicine Lead Researcher: San Román del Barrio, Julio
Group members
STAFF MEMBERS: Castellanos Páez, Aida | Fernández Gutierrez, María del Mar | Parra Cáceres, Juan. ASSOCIATED MEMBERS: Aguilar de Armas, Ma Rosa | Domingo Pascual, Concepción | González Gómez,
Álvaro | Ramírez Jiménez, Rosa Ana | Rodríguez Crespo, Gema | Rodríguez Lorenzo, Luis | Vázquez Lasa, Blanca. CONTRIBUTORS: Palao Suay, Raquel | Parra Ruiz, Francisco Jesús.
Main lines of research
• Preparation of selfcuring polymeric systems for surgery. The line is centered in the development of selfcuring polymer systems of low toxicity, high biocompatibility for application for the bi- omechanical stabilization of prosthesis and as controlled delivery systems of bioactive com- pounds (antibiotics, bactericide, anti-inflammato- ry agents, antithromobgenic).
• Polymer Drugs anjd targeting systems. Prepara- tion of bioactive polymer systems with targeting properties for the application and release of well- known bioactive compounds with anti-inflamma- tory action, antithrombogenic, antiproliferative, antioxidant. This is one of the mean lines of the group, with cooperation with companies of the biomedical and pharmaceutical fields. Bioactive polymer systems have been designed for bioac- tive coatings of drug eluted stents DES for coro-
nary treatment, bioactive abdominal meshes with antibiotic action at local level (targeting), intraoc- ular lenses with controlled proliferative action and antiangiogenic actions, polymer drugs with low toxic action for cancer therapy.
• Biodegradable polymer systems for surgery and pharmacy. Design and development of resorb- able polymer systems as porous scaffolds of great interest in processes of tissue regenera- tion (Tissue Engineering). The polymer systems offers wide spectra of formulations with hydro- phobic or hydrophilic character, which allows the preparation of 3D scaffolds to be applied in regeneration of bone tissue, epidermal or con- nective tissues, with specific properties. Several patents have been registered and are on transfer processes to several companies of the biomedi- cal device sector.
100 I Annual report 2015 I CIBER-BBN