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leaD reSearcher
Pedraz Muñoz, José Luis
Universidad del País Vasco
Facultad de Farmacia
Paseo de la Universidad, 7 01006 Vitoria / Gasteiz | Álava
(+34) 94 501 30 91 [email protected] group Website
GROUP MEMBERS
Staff members: Cañibano Hernández, Alberto | Ciriza Astrain, Jesús | Espona Noguera, Albert | Losada Narváez, Ángela
Associated members: Acarregui Garalde, Argia | Agirre Díez, Mireia | Esquisabel Alegría, Amaia | Hernández Martín, Rosa María | Igartúa Olaechea, Manoli | Orive Arroyo, Gorka | Puras Ochoa, Gustavo | Sáenz del Burgo Martínez, Laura | Salvador Martínez, Aiala | Santos Vizcaíno, Edorta | Zárate Sesma, Jon
Main lines of research
• Microencapsulation of alive cells: Design and optimization of polymeric systems for immobilization of cells with therapeutic activity. This system provides protection to cells against the host’s immune response due to its technological design, and at the same time, it turns into a controlled release pharmaceutical system.
• Micro and nano-particles as vaccine administration systems of peptides and proteins: Promising results obtained by our research group support the use of these drug (antigen) carrier systems to develop vaccines, as demonstrated by the results after their administration by different routes in laboratory animals (mice and monkeys), inducing a sustained and strong immune response.
• Non-viral vectors for gene therapy purposes: Design and optimization of non-viral vectors based on lipidic and polymeric nanoparticles to transfect eukaryotic cells with therapeutic genes.
• Development of modified release formulations: Development and optimization of drug delivery systems based on new polymers to obtain a sustained release profile of drugs.
• Pharmacocinetic and biopharmaceutical evaluation of modified drug delivery and therapeutic 84
PROGRAMMES
Nanomedicine