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Most relevant scientific articles
• Aznar E., Oroval M., Pascual L., Murguía J.R., Martínez-Manez R., Sancenón F. Gated Materials for On- Command Release of Guest Molecules. Chemical Reviews. 2016;116(2):561-718.
• Díez P., Sánchez A., De La Torre C., Gamella M., Martínez-Ruiz P., Aznar E. et al. Neoglycoenzyme- Gated Mesoporous Silica Nanoparticles: Toward the Design of Nanodevices for Pulsatile Programmed Sequential Delivery. ACS Applied Materials and Interfaces. 2016;8(12):7657-7665.
• Oroval M., Coronado-Puchau M., Langer J., Sanz-Ortiz M.N., Ribes A., Aznar E. et al. Surface Enhanced Raman Scattering and Gated Materials for Sensing Applications: The Ultrasensitive Detection of Mycoplasma and Cocaine. Chemistry - A European Journal. 2016.
• Ribes A., Xifre-Pérez E., Aznar E., Sancenón F., Pardo T., Marsal L.F. et al. Molecular gated nanoporous anodic alumina for the detection of cocaine. Scientific Reports. 2016;6.
• Polo L., Gómez-Cerezo N., Aznar E., Vivancos J.-L., Sancenón F., Arcos D. et al. Molecular gates in mesoporous bioactive glasses for the treatment of bone tumors and infection. Acta Biomaterialia. 2016.
Highlights
During 2016, we began the intramural projects NANOPROBE, NANOTARGET, GBM ON CHIP, the new editions of the projects NANOHYPERTERMIA and SPRING and the collaborative project “Search for biomarkers for the early detection of Alzheimer’s disease in the Vallecas project cohort”. In addition, we have continued with the development of MICHORMON-PRO and AUDIOMC transfer projects and the SEPAR-CIBERES- CIBERBBN TARMAC project. In the framework of all these projects, we have developed different systems applied to both therapy and disease diagnosis. In addition, we have started our new project of the National plan on intelligent nanomaterials, probes and devices for the integrated development of new tools applied to the biomedical field, a new RETOS project and two joint projects between researchers of the Polytechnic University of Valencia and IIS La Fe for the establishment of a smart drug discovery platform and for the development of a new kit for the detection of candida.
Like other years, we have continued with an intense scientific activity publishing 31 articles in international journals with high impact factor. Among them, we can highlight the works dealing with ultrasensitive detection using gated nanoparticles and SERS, in collaboration with the group of Luís M. Liz-Marzán or the development of a system for the treatment of infections and bone tumors using bioactive mesoporous glasses combined with molecular gates, in collaboration with the group of María Vallet.
At international level, we have continued with the development of the NANOTUN3D project. In addition, we have hosted five students and researchers from India, Czech Republic, France and Italy. In addition, three of our predoctoral students have been in Ireland for short stays.
Finally, in 2016 our group has also had an intense formative activity. We participated in the CIBER-BBN training program where one of our students got a research initiation grant and later a pre-doctoral fellowship from the Universitat Politècnica de València. In addition, six of our students have defended their doctoral thesis during this year.
BBN
Research Groups 79