Page 49 - CIBER-BBN2016-ENG

Most relevant scientific articles
• Oliveira H., Catros S., Boiziau C., Siadous R., Martí-Munoz J., Bareille R. et al. The proangiogenic potential of a novel calcium releasing biomaterial: Impact on cell recruitment. Acta Biomaterialia. 2016;29:435-445.
• Gugutkov D., Gustavsson J., Cantini M., Salmerón-Sánchez M., Altankov G.. Electrospun fibrinogen- PLA nanofibres for vascular tissue engineering. Journal of Tissue Engineering and Regenerative Medicine. 2016.
• Vila M., García A., Girotti A., Alonso M., Rodríguez-Cabello J.C., González-Vázquez A. et al. 3D silicon doped hydroxyapatite scaffolds decorated with Elastin-like Recombinamers for bone regenerative medicine. Acta Biomaterialia. 2016;45:349-356.
• Vila O.F., Garrido C., Cano I., Guerra-Rebollo M., Navarro M., Meca-Cortes O. et al. Real-time bioluminescence imaging of cell distribution, growth, and differentiation in a three-dimensional scaffold under interstitial perfusion for tissue engineering. Tissue Engineering - Part C: Methods. 2016;22(9):864-872.
• Forget J., Awaja F., Gugutkov D., Gustavsson J., Gallego Ferrer G., Coelho-Sampaio T. et al. Differentiation of Human Mesenchymal Stem Cells Toward Quality Cartilage Using Fibrinogen-Based Nanofibers. Macromolecular Bioscience. 2016;:1348-1359.
Highlights
Among our lines of research, we have worked on microparticles to produce new bioinks to print organs such as bone and produce microtissues as systems to model pathologies like cancer. This project has been funded by MINECO.
A project for transference related to a new dressing to treat chronic and diabetic ulcers (Dermoglass) have been funded for the first edition of CAIXAIMPULSE, a new program supported by Obra Social La Caixa to bring science to the market. Next year we will be able to test our product in large animals and a patent is being prepared to protect the invention. Moreover, this project obtained an award from the EITHealth to help for the IP protection and the scalability studies and commercialization of the product.
Within an intramural project, in collaboration with the group of Prof. Rodriguez-Cabello from the University of Valladolid, the group developed microstructured biomimetic hydrogels using new crosslink methods that induce bone formation in in vivo models. These biomaterials have also been combined with 3D printed hydroxyapatite scaffolds to enhance bone formation in collaboration with Prof. Vallet and Prof. Bujan.
We have also collaborated with a group of traumatologists in Vall d’Hebron Hospital to produce microstructured materials to heal bone fractures by the enhancement of angiogenesis and osteogenesis. Three new intramural projects have started related to bone and cardiac regeneration and cancer therapies.
BBN
Research Groups 49