Page 41 - CIBER-BBN2016-ENG

Most relevant scientific articles
• Orgaz F., Dzika A., Szycht O., Amat D., Barba F., Becerra J. et al. Surface nitridation improves bone cell response to melt-derived bioactive silicate/borosilicate glass composite scaffolds. Acta Biomaterialia. 2016;29:424-434.
• Jara N., Cifuentes M., Martínez F., Salazar K., Nualart F. Cytoarchitecture, Proliferative Activity and Neuroblast Migration in the Subventricular Zone and Lateral Ventricle Extension of the Adult Guinea Pig Brain. Stem Cells. 2016.
• Visser R., Rico-Llanos G.A., Pulkkinen H., Becerra J. Peptides for bone tissue engineering. Journal of Controlled Release. 2016;244:122-135.
• Lagunas A., Tsintzou I., Vida Y., Collado D., Pérez-Inestrosa E., Pereira C.R. et al. Tailoring RGD local surface density at the nanoscale toward adult stem cell chondrogenic commitment. Nano Research. 2016;:1-13.
• Visser R., Bodnarova K., Arrabal P.M., Cifuentes M., Becerra J. Combining bone morphogenetic proteins-2 and -6 has additive effects on osteoblastic differentiation in vitro and accelerates bone formation in vivo. Journal of Biomedical Materials Research - Part A. 2016;104(1):178-185.
Highlights
In 2016 we have partnered with groups and companies from Rizzoli Orthopaedic Institute (Italy); Italian National Research Council – CNR (Italy); TecMinho (SME) (Portugal) and Spain to submit the proposal “Tailored photo-active Keratin nanofibres as advanced wound Dressings” to the Horizon 2020 PROPOSAL N°37, EURONANOMED II Joint Transnational Call for Proposals (2016) for “EUROPEAN INNOVATIVE RESEARCH & TECHNOLOGICAL DEVELOPMENT PROJECTS IN NANOMEDICINE. We have as well applied for funding from Call: H2020-MSCA-IF-2016, presenting the proposal “Osteoinductive functionalization of biomaterials with biomimetic peptides containing specific binding domains or with nanotechnological graphene coating for bone tissue engineering, SILKOGRAPH”.
We have obtained funding from the Instituto de Salud Carlos III through the RETICS call, being accepted our membership into de Network of Cell Therapy (TerCel) for the next 5-year period 2017-20.
We have also obtained funding from the Andalusian Regional Government “Desarrollo de un Preparado de Ingeniería Tisular para el tratamiento de Osteonecrosis Maxilar Aséptica” (PI-0339-2014), IP: Rick Visser.
The article Act Biomaterialia 29:424-34 quickly getting much attention from the media, and being Dr. Leonor Santos-Ruiz (CIBER-BBN researcher) interviewed in several radio and TV programmes.
In collaboration with Cell Therapy Network (TerCel), our group has joined a team that leads two Clinical Assays:
• “Treatment Of Maxillary Bone Cysts With Autologous Bone Mesenchymal Stem Cells (MSV-H) (BIOMAX)”
(NCT01389661).
• “Intravenous Infusion of Fucosylated Phase I Clinical Trial to Evaluate The Intravenous Infusion Of
Autologous Fucosylated Bone Marrow Mesenchymal Cells Therapy In Patients With Established Osteoporosis” (NCT02566655).
BBN
Research Groups 41