Page 36 - CIBERBBN-2015-eng

Research groups
Research Group in Biomedical Applications
of Nuclear Magnetic Resonance
Programme: Bioengineering & Medical Image Lead Researcher: Arús Caralto, Carles
Group members
STAFF MEMBERS: Candiota Silveira, Ana Paula | Juliá Sapé, Ma Margarita.
ASSOCIATED MEMBERS: Acebes Martín, Juan José | Aguilera Grijalbo, Carlos | Arias Ramos, Nuria | Baquero Munera, Miguel | Cabañas Egaña, Miquel | Capdevila Cirera, Antonio | Cos Domingo, Mónica | Fernández Flores, Francisco | Ferrer Font, Laura | Lope Piedrafita, Silvia | Majos Torro, Carlos | Mocioiu, Víctor | Moreno Torres, Ángel | Oriol Rocafiguera, Albert | Pumarola I Battle, Martí | Vellido Alcacena, Alfredo.
CONTRIBUTORS: Ciezka, Magdalena | Fernández Coello, Alejandro | Ortega Martorell, Sandra. Main lines of research
The major research interest of our group is to im- prove the diagnosis, treatment and follow-up of therapy response of abnormal brain masses, with noninvasive monitoring tools based in Nuclear Mag- netic Resonance (NMR). Within this major goal, sev- eral sublines related to MR methodology are being investigated, which include:
• Characterization of the type and grade of human brain tumors and other neural pathologies by imaging (MRI) and in vivo magnetic resonance spectroscopy (MRS, MRSI).
• Classifier development and their implementation into decision-support systems (DSS) for helping in clinical decision making in an evidence-based medicine context.
• Treatment and follow-up of preclinical brain tu- mour models with novel therapeutic agents.
• Search for molecular biomarkers of in vivo tumor therapy response, with the help of ex vivo and in vitro studies of cell models, animal models and their biopsies. Correlation with molecular and cel- lular parameters (histopathology, genomics).
• In vivo molecular phenotyping of tumor progres- sion and therapy response.
36 I Annual report 2015 I CIBER-BBN