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leaD reSearcher
Sanz Carrasco, Fausto
Universidad de Barcelona
Facultad de Química. Edificio Hélix,
C/ Baldiri Reixac, 10-12 08028 Barcelona
[email protected]
GROUP MEMBERS
Staff members: Camarero Palao, Núria | Giannotti, Marina Inés
Associated members: Díez Pérez, Ismael | Gorostiza Langa, Pau | Torrent Burgues, Joan
Contributors: Cortijos Aragonés, Albert | López Martínez, Montserrat | Oliva Herrera, Mireia | Pozuelo Ruiz, Marta
Main lines of research
• Electrochemical STS of biomimetic membranes with redox systems. Measuring the energy levels of a protein under a variety of experimental conditions (in the presence of illumination or certain cofactors and partner proteins) will provide new insights into the detailed electron transfer mechanisms.
• Mechanical stability at the molecular level. Nanomechanics of lipid bilayers and other biosystems. Understanding the effect of mechanical stress on biological membranes is of fundamental importance since cells are known to naturally perform their function under the effect of a complex combination of forces.
• Development and application of light-activated nanoswitches to control the activity of protein complexes and cells. We will develop new optical switches (like the light-gated glutamate receptor LiGluR) in order to study the processes involved in neurosecretion, exocytosis and endocytosis.
• Vectorization of therapeutically active molecules. We prepare and characterize therapeutic agent (drugs, peptides, proteins, genetic material...) release systems based on supramolecular conjugates which allow reaching the point of action in a directed and effective manner.
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PROGRAMMES
Nanomedicine